AP Top 25: College Football's Biggest Upsets & Must-Watch Matchups (2025)

The AP Top 25 rankings just got a whole lot more exciting! But here's where it gets controversial—unranked teams are making their mark, and the underdogs are biting back.

Louisville's Shocking Upset: In a stunning turn of events, Louisville took down the mighty No. 2 Miami, intercepting four passes from Carson Beck en route to a 24-21 victory. This unexpected result will undoubtedly shake up the rankings, with Louisville poised to make a dramatic entrance. And this is the part most people miss—the Cardinals' success wasn't a fluke. They've been building momentum, and their strategy paid off big time.

SEC Showdowns: The Southeastern Conference took center stage with three of the five AP Top 25 matchups. The spotlight game was a top-10 clash between No. 5 Mississippi and No. 9 Georgia, a rivalry with a long history. Mississippi, seeking to break a 26-year drought, faced a Georgia team aiming to improve on recent performances. Meanwhile, LSU visited Vanderbilt, Tennessee faced a tough test at Alabama, and Utah battled BYU.

Key Matchups to Watch:
1. Mississippi vs. Georgia: QB Trinidad Chambliss faces a challenging road debut, as Mississippi aims to break their losing streak at Georgia. The Rebels' recent win over Washington State was underwhelming, while Georgia struggled in their previous game against Auburn. Can Chambliss lead his team to an upset? BetMGM Sportsbook favors Georgia by 7.5.
2. Tennessee vs. Alabama: A battle of SEC QB talents, Tennessee's Joey Aguilar and Alabama's Ty Simpson, a Heisman Trophy favorite, go head-to-head. Tennessee's defense will be tested, as they've struggled to stop opponents. Can they pull off an upset in Tuscaloosa? BetMGM Sportsbook predicts Alabama by 8.5.
3. LSU vs. Vanderbilt: QBs Garrett Nussmeier and Diego Pavia seek consistency. Nussmeier, an early Heisman contender, has been inconsistent due to injuries. Pavia had a rough outing against Alabama. Which QB will rise to the occasion? BetMGM Sportsbook gives Vanderbilt a slight edge, favoring them by 2.5.

Other Notable Games:
- Southern California vs. Notre Dame: A heated rivalry with playoff implications. USC's high-powered offense faces Notre Dame's stout defense. The Trojans have a tough road ahead, while Notre Dame aims to bounce back from recent losses. A must-win for both teams. BetMGM Sportsbook favors Notre Dame by 9.5.
- Utah vs. BYU: The Holy War rivalry intensifies as a Big 12 game. BYU looks to extend their winning streak against Utah, thanks to a controversial penalty last year. Will Utah seek revenge? BetMGM Sportsbook predicts a close game, favoring Utah by 3.5.
- Washington vs. Michigan: A potential Top 25 entry, this game could see Washington rise or Michigan reclaim their spot. Washington, coming off a win over Rutgers, faces a Michigan team eager to recover from a loss to USC. Who will prevail? BetMGM Sportsbook leans towards Michigan by 5.5.

Stay tuned as the AP Top 25 continues to unfold, and feel free to share your predictions and opinions in the comments. Which unranked teams will make a statement? Will the underdogs continue to surprise? Let the debates begin!

AP Top 25: College Football's Biggest Upsets & Must-Watch Matchups (2025)
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